Honoring Nelson YS Kiang
Nelson YS Kiang, PhD, founder of the Eaton-Peabody Laboratories and Professor Emeritus of Physiology at Harvard Medical School, passed away at the age of 93.
Tag: Harvard Medical School
All
Latest
All
Latest
Frequency Therapeutics Appoints Kevin Franck as SVP
Dr Franck will lead pre-commercial strategy and launch planning for Frequency’s clinical pipeline, including its lead program aimed at developing a restorative treatment for sensorineural hearing loss (SNHL), the most common form of hearing loss.
All
Latest
New Hearing Test May Help Diagnose Meniere’s Disease Earlier
Lichtenhan and colleagues have now used the new test to detect early low-frequency hearing loss in an animal model of Meniere’s disease, a poorly understood condition characterized by hearing loss, tinnitus, and episodic vertigo.
Researchers Develop ‘Optimized’ Gene-Editing System to Help Prevent Hearing Loss in Mice
Utilizing a more “precise” version of the CRISPR-Cas9 gene-editing system, scientists from Harvard Medical School and Boston Children’s Hospital were able to turn off the defective TMC1 gene that causes hearing loss, leaving the healthy copy unaffected.
Read More
Researchers Develop ‘Optimized’ Gene-Editing System to Help Prevent Hearing Loss in Mice
Utilizing a more “precise” version of the CRISPR-Cas9 gene-editing system, scientists from Harvard Medical School and Boston Children’s Hospital were able to turn off the defective TMC1 gene that causes hearing loss, leaving the healthy copy unaffected.
Read More
Mechanism Helps Explain the Ear’s Exquisite Sensitivity
The human ear, like those of other mammals, is so extraordinarily sensitive that it can detect sound-wave-induced vibrations of the eardrum that move by less than the width of an atom. Now, researchers at MIT have discovered important new details of how the ear achieves this amazing ability to pick up faint sounds.
Read More
Researchers Raise Concerns about Telehealth Data Transmission
With the majority of telehealth consultations occurring in the home, sessions offered through smart home devices could create a channel where both consumer and healthcare data flow seamlessly through one device back to a commercial retailer.
Read More
University of Rochester Researchers Regrow Sensory Hair Cells
The researchers found that activating the ERBB2 pathway triggered a cascading series of cellular events by which cochlear support cells began to proliferate and start the process of activating other neighboring stem cells to become new sensory hair cells.
Read More
Research Study Finds Neurogenesis Can Help Improve Cognitive Function in Mouse Model of Alzheimer’s
The investigation shows that the beneficial effects on cognition can be blocked by the hostile inflammatory environment present in the brains of patients with Alzheimer’s disease and that physical exercise can “clean up” the environment, allowing new nerve cells to survive, thrive, and improve cognition in the Alzheimer’s mice.
Read More
Harvard Medical School Researchers Find Sensory Protein Linked to Hearing and Balance
The results of their research, reported August 22 in “Neuron,” reveal that TMC1, a protein discovered in 2002, forms a sound- and motion-activated pore that allows the conversion of sound and head movement into nerve signals that travel to the brain—a signaling cascade that enables hearing and balance.
Read More
Akouos Raises $50 Million in Series A Financing; Forms Scientific Advisory Board
Akouos is developing targeted adeno-associated viral vector (AAV)-based gene therapies for sensorineural hearing loss, which results from dysfunction or damage to sensory cells and/or nerve fibers of the inner ear.
Read More
Frequency Therapeutics Announces Phase 1/2 Clinical Trial for Hearing Restoration Drug
Progenitor Cell Activation (PCA) utilizes small molecules to awaken dormant progenitor cells already in the body and reportedly has the opportunity to address numerous degenerative diseases such as hearing loss, demyelinating diseases, skin disorders, and gastrointestinal conditions.
Read More
Mifepristone May Halt Growth of Tumor That Causes Hearing Loss
Currently, patients with symptomatic or growing vestibular schwannomas can undergo surgical resection (through craniotomy) or radiation therapy; however, both of these procedures come with significant risks.
Read More
Akouos Announces $7.5 Million Seed Round, Strategic License Agreement for Hearing Disorder Gene Therapy Platform
Anc-AAVs are in silico-designed adeno-associated viral vectors (AAVs), first developed in the laboratory of Dr Luk H. Vandenberghe, assistant professor of ophthalmology at Harvard Medical School, and director of the Grousbeck Gene Therapy Center at Massachusetts Eye and Ear.
Read More
Mass. Eye and Ear Receives Gift Totaling More Than $20 Million for Hearing Research
This gift reportedly represents one of the country’s largest philanthropic investments ever to advance research on hearing and hearing loss, a significant public health problem impacting one-third of the world’s population over age 65.
Read More
Inner Ear Tissue Grown from Human Stem Cells
Researchers at Indiana University School of Medicine have successfully developed a method to grow inner ear tissue from human stem cells—a finding that could lead to new platforms to model disease and new therapies for the treatment of hearing and balance disorders.
Read More
2017 Callier Prize Awarded to Sharon Kujawa for Research on Hidden Hearing Loss
Sharon G. Kujawa, an auditory neuroscientist who studies how aging and noise exposure can impact hearing, has been selected to receive the biennial Callier Prize in Communication Disorders for her research into the connections between the hair cells and the nerve fibers (synapses) that are most vulnerable—what is now being referred to as “hidden hearing loss.”
Read More
Two Studies Detail Improved Gene Therapy for Hearing Restoration in Mice
Two new papers published in Nature Biotechnology on February 6 detail research by scientists at Boston Children’s Hospital—a pediatric teaching hospital affiliated with Harvard Medical School—on an improved gene therapy that helps restore hearing to genetically deaf mice.
Read More