Researchers Advance Gene Therapy for CLIC5-Related Inner Ear Dysfunction
The therapy targets mutations in the CLIC5 gene, which affect hair cell stability and lead to progressive hearing and balance impairments.
Category: Sensorineural
Sensorineural
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Sensorineural
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Gold Standard Treatment for Sudden Sensorineural Hearing Loss
In this case study, a man with hearing loss after a stroke benefits from hyperbaric oxygen therapy and steroid treatments.
Sensorineural
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COVID-19 Associated with Hearing Loss, Study Shows
Hearing loss and other auditory problems are strongly associated with COVID-19 according to a systematic review of research evidence.
What Is “Normal Hearing” for Older Adults and Can “Normal-hearing Older Adults” Benefit from Hearing Care Intervention?
Researcher and author Larry Humes, PhD, points out that large-scale studies have identified self-reported hearing difficulties as one of the strongest predictors of hearing aid uptake and use. He says this further reinforces the need for the older consumer and the hearing care professional to quantify the severity of hearing difficulties above and beyond those captured by the pure-tone audiogram.
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BBC Looks at How Loud Music Can Lead to Early Signs of Hearing Damage
The article examined a study from researchers at the University of Manchester, which suggests that although the damage observed is not enough to be diagnosed as a full-blown hearing loss, it could potentially have a cumulative effect on hearing later in life.
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Researchers Look at Potential Link between Coronavirus and Hearing Loss
The authors point out that coronaviruses, in some cases, can cause peripheral neuropathy, and, ”in theory..COVID-19 could cause auditory neuropathy, a hearing disorder where the cochlea is functioning but transmission along the auditory nerve to the brain is impaired.”
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The Musicians’ Clinics of Canada Launches New Website
MusiciansClinics.com is a resource for those seeking information on a variety of topics related to hearing and hearing loss in musicians. Developed by audiologist-musician Marshall Chasin, AuD, the website offers a large range of resources for guitarists, bass players, violinists, woodwind players, school band teachers, and more.
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USC Stem Cell Study Traces Evolution of Organ of Corti
By the time mice are born, the progenitor cells in the Organ of Corti have finished both proliferation and differentiation, and cannot regenerate if they are damaged—causing permanent hearing loss.
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Age-related Hearing Loss Genes Discovered in Fruit Flies
“Our twin discoveries that fruit flies experience age-related hearing loss and that their prior auditory health is controlled by a particular set of genes, is a significant breakthrough. The fact that these genes are conserved in humans will also help to focus future clinical research in humans and thereby accelerate the discovery of novel pharmacological or gene-therapeutic strategies,” says lead-author Joerg Albert.
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Age-related Hearing Loss May Reorganize Brain’s Sensory Areas
Researchers looked at mice engineered to have progressive hearing loss, and found that their neurotransmitter receptors—responsible for communication between brain cells—exhibited changes in sensory processing regions related to memory.
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Researchers Chart Development of Cells from Mouse Cochlea
In the future, scientists may be able to use the data to steer stem cells toward the hair cell lineage, helping to produce the specialized cells they need to test cell replacement approaches for reversing some forms of hearing loss.
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Sonova Announces New Brand Ambassador, Volleyball Player Natália Martins
The 35-year-old has had profound hearing loss since childhood and wears hearing aids from Sonova brand, Phonak. In Brazil, she is the “first volleyball player with hearing loss to play at professional level and to make it into her country’s national team.”
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Frequency Therapeutics Announces Clinical Data from Auditory Drug
FX-322 is Frequency’s lead product candidate, designed to regenerate auditory sensory hair cells in the cochlea and improve hearing in patients with sensorineural hearing loss (SNHL).
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Researchers Examine Link Between Cognitive Decline, Hearing Loss
In the hippocampus, synaptic plasticity was chronically impaired by progressive hearing loss. The distribution and density of neurotransmitter receptors in sensory and memory regions of the brain also changed constantly. The stronger the hearing impairment, the poorer were both synaptic plasticity and memory ability.
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How Might the Brain Change When We Reintroduce Sound? Interview with Anu Sharma, PhD
New research shows that after wearing professionally fit quality hearing aids, a patient’s brain may “re-organize” its auditory processing centers back towards its original state prior to the hearing loss—with corresponding gains in auditory speech perception abilities and improvements in global cognitive function, executive function, processing speed, and visual working memory performance. Anu Sharma discusses the research findings with Douglas Beck.
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Moving Past the First Fit Approach and Modernizing the Hearing Healthcare Space
Adapting the “first fit” experience to be more reflective of a patient’s gradual hearing loss experience and providing for a gradual transition allows the auditory system to receive, process, and accept sounds that have been missing.
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Psychoacoustics: Auditory Perception in Normal and Impaired Hearing: Interview with Jennifer Lentz, PhD
As hearing aid processing becomes more complex, the area of psychoacoustics becomes increasingly important for understanding exactly what these devices are doing (or trying to do) for your patients’ compromised auditory systems.
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Children and the Development of Listening and Talking Skills: An Interview with Carol Flexer, PhD
Dr Flexer is an expert in the development and expansion of listening, speaking, and literacy skills in infants and children, including those with all degrees of hearing loss.
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