Regeneron’s Gene Therapy DB-OTO Trial Shows Promising Hearing Improvement
Investigational gene therapy DB-OTO showed promising improvements in hearing and speech development in children with otoferlin-related genetic hearing loss.
Category: Sensorineural
Sensorineural
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Sensorineural
Latest
Delta Variant of COVID-19 May Cause Hearing Loss
Hearing impairment, blood clots leading to gangrene, and “severe gastric upsets,” are being seen by doctors in India, England, and Scotland, where the B.1.617.2 delta strain is prevalent and more likely to lead to hospitalization, Bloomberg reported.
Sensorineural
Latest
Research Shows Hair Cell Damage May Be Main Cause of Age-related Hearing Loss
Researchers examined 120 inner ears collected at autopsy. They used multivariable statistical regression to compare data on the survival of hair cells, nerve fibers, and the stria vascularis with the patients' audiograms to uncover the main predictor of the hearing loss in this aging population. They found that the degree and location of hair cell death predicted the severity and pattern of the hearing loss, while stria vascularis damage did not.
Age-related Hearing Loss May Reorganize Brain’s Sensory Areas
Researchers looked at mice engineered to have progressive hearing loss, and found that their neurotransmitter receptors—responsible for communication between brain cells—exhibited changes in sensory processing regions related to memory.
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Researchers Chart Development of Cells from Mouse Cochlea
In the future, scientists may be able to use the data to steer stem cells toward the hair cell lineage, helping to produce the specialized cells they need to test cell replacement approaches for reversing some forms of hearing loss.
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Sonova Announces New Brand Ambassador, Volleyball Player Natália Martins
The 35-year-old has had profound hearing loss since childhood and wears hearing aids from Sonova brand, Phonak. In Brazil, she is the “first volleyball player with hearing loss to play at professional level and to make it into her country’s national team.”
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Frequency Therapeutics Announces Clinical Data from Auditory Drug
FX-322 is Frequency’s lead product candidate, designed to regenerate auditory sensory hair cells in the cochlea and improve hearing in patients with sensorineural hearing loss (SNHL).
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Researchers Examine Link Between Cognitive Decline, Hearing Loss
In the hippocampus, synaptic plasticity was chronically impaired by progressive hearing loss. The distribution and density of neurotransmitter receptors in sensory and memory regions of the brain also changed constantly. The stronger the hearing impairment, the poorer were both synaptic plasticity and memory ability.
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How Might the Brain Change When We Reintroduce Sound? Interview with Anu Sharma, PhD
New research shows that after wearing professionally fit quality hearing aids, a patient’s brain may “re-organize” its auditory processing centers back towards its original state prior to the hearing loss—with corresponding gains in auditory speech perception abilities and improvements in global cognitive function, executive function, processing speed, and visual working memory performance. Anu Sharma discusses the research findings with Douglas Beck.
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Moving Past the First Fit Approach and Modernizing the Hearing Healthcare Space
Adapting the “first fit” experience to be more reflective of a patient’s gradual hearing loss experience and providing for a gradual transition allows the auditory system to receive, process, and accept sounds that have been missing.
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Psychoacoustics: Auditory Perception in Normal and Impaired Hearing: Interview with Jennifer Lentz, PhD
As hearing aid processing becomes more complex, the area of psychoacoustics becomes increasingly important for understanding exactly what these devices are doing (or trying to do) for your patients’ compromised auditory systems.
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Children and the Development of Listening and Talking Skills: An Interview with Carol Flexer, PhD
Dr Flexer is an expert in the development and expansion of listening, speaking, and literacy skills in infants and children, including those with all degrees of hearing loss.
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Managing People with Sensorineural and Conductive Unilateral Hearing Loss and Single-Sided Deafness
CROS and BiCROS hearing aids are not the only treatment options for those with unilateral hearing loss. This article reviews other options and potential future avenues for unilateral sensorineural hearing loss and single-sided deafness, as well as for unilateral conductive hearing loss.
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New Texas Law Allows Individuals to Indicate Hearing Difficulties on Vehicle Registration
Senate Bill 976 aims to clear up any miscommunication that may occur during a traffic stop, as the health information will be available to an officer who runs the license plate through their system.
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Testing for Cochlear Dead Regions Using a Piano
Audiologist Marshall Chasin posits a simple test that can be employed with a piano or keyboard that might quickly screen people for the possibility of a cochlear dead zone.
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Speech in Noise Research and Deep Neural Networks: An Interview with Lars Bramslow, PhD
A discussion of the speech-in-noise problem, why directional microphones often fall short in real-life listening situations, and how one of the more interesting areas of hearing aid research involves the idea of deep neural networks (DNN).
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Blog: FDA to Issue First Proposed Rules on OTC Hearing Aids in November
It now appears the “OTC regulatory debate” could potentially follow the same general timeframe as the 2020 presidential race—starting with proposed rules by the FDA in November of this year.
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Osteoporosis May Increase Risk of Sudden Sensorineural Hearing Loss, Study Shows
The researchers found that 0.8% of those with osteoporosis and 0.5% of adults in the control group without the condition experienced sudden sensorineural hearing loss. This means that people with osteoporosis have a 40% increased risk of developing a sudden sensorineural hearing.
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