Tag: Massachusetts Eye and Ear

Brain Plasticity Compensates for Damaged Auditory Nerve Fibers

Massachusetts Eye and Ear and Harvard researchers have described, for the first time, the adult brain’s ability to compensate for a near-complete loss of auditory nerve fibers that link the ear to the brain…an imperfect hearing recovery process that may explain why some patients report difficulties understanding speech despite having normal hearing thresholds.

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Device Could Help Target Delivery of Hearing Loss Drugs

Several pharmaceutical companies are developing drugs that have potential to treat hearing loss, but they often encounter difficulty demonstrating preclinical efficacy due to challenges regarding concentration of the medication at the intended delivery site. Now researchers have developed a device that can deliver drugs directly to the cochlea—an area of the inner ear difficult to reach with injections and systemic drug delivery.

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Mouse Study Shows Sound Deprivation Causes Hearing Loss

Massachusetts Eye and Ear researchers have shown that sound deprivation in adult mice causes irreversible damage to the inner ear. The findings, as outlined in the November 18, 2015 edition of PLoS One, suggest that chronic conductive hearing loss, such as that caused by recurrent ear infections, leads to permanent hearing impairment if it remains untreated.

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Boston Marathon Bombing Survivors Suffer Ongoing Ear and Hearing Problems

A research report from Massachusetts Eye and Ear Institute (MEEI) and Harvard Medical School, outlines the ear and hearing problems suffered by surviving victims of the bomb explosions at the April 15, 2013 Boston Marathon. The research report describes the types of otologic injuries people sustained in the tragedy, and the outcomes of the patients undergoing continued otologic treatment.

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