New Drug Delivery System Developed for Chemo-Induced Hearing Loss
The novel drug delivery system uses hydrogels and nanoparticles to protect against hearing loss caused by the chemotherapy drug cisplatin.
Tag: chemotherapy
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Chemotherapy Drug More Harmful to Young Children
A chemotherapy drug known to cause hearing loss in children is more likely to do so the earlier in life children receive it, new University of British Columbia (UBC) research published on its website has found.
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Dabrafenib May Help to Protect Hearing, Researchers Say
The findings are significant because no such FDA-approved drug currently exists, and the drug that has shown effectiveness to protect hearing in animal models in the study, dabrafenib, is an FDA-approved drug that is currently used in treating cancers.
Fennec Announces FDA Filing Acceptance for Ototoxicity Drug, Pedmark
PEDMARK is said to be an investigational drug for the prevention of ototoxicity induced by cisplatin chemotherapy in patients one month to <18 years of age with localized, non-metastatic, solid tumors.
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Education May Help Cancer Survivors Cope with Hearing Loss
Researchers involved with a qualitative study published in Cancer concluded that clinicians play...
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Sensorion Receives European Medicines Agency Approval for PIP on Hearing Loss Treatment
SENS-401 is under development in the treatment of Sudden Sensorineural Hearing Loss (or SSNHL).
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Sensorion Receives European Medicines Agency Approval for PIP on Hearing Loss Treatment
SENS-401 is under development in the treatment of Sudden Sensorineural Hearing Loss (or SSNHL).
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Otonomy Announces Upcoming Presentations at 42nd ARO MidWinter Meeting
“Our multiple presentations at ARO demonstrate our broad pipeline in neurotology with data presented in support of our product candidates for Ménière’s disease, tinnitus, hearing loss, and otoprotection,” said Kathie Bishop, PhD, chief scientific officer of Otonomy.
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University of Connecticut Researchers Find Protein Connected with Hearing Loss
UConn otolaryngologist Kourosh Parham and his colleagues report in “Hearing Research” that levels of prestin, a protein found only in cells in the inner ear, rise sharply when those cells are damaged and start to die.
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New Research Highlights Outcomes of Ida Institute’s Methods and Tools
Since 2016, the Ida Institute Research Committee has awarded research grants to projects that investigate the outcomes of using Ida Institute methods and tools and develop evidence to show the effect of person-centered hearing care.
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Webinar on Pediatric Chemo-Induced Hearing Loss to Be Held September 13
This half-day event follows the Food and Drug Administration’s (FDA) model for externally-led Patient Focused Drug Development meetings and serves to inform the agency’s regulatory decision-making in pediatric oncology.
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Sensorion Receives Approval for SENS-401 Phase 2 Clinical Trial
The randomized, double-blind, placebo-controlled Phase 2 study will be conducted across 50 sites in Europe, the US, Canada, Israel, and Turkey, and enroll approximately 260 patients.
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Sodium Thiosulfate May Help Reduce Cisplatin-Related Hearing Loss, New Study Says
The study showed that STS administered six hours after Cisplatin could reduce the severity of hearing loss without affecting the chance of cure for the cancer.
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Fennec Pharmaceuticals’ Cisplatin-Ototoxicity Treatment Given Breakthrough Therapy Designation
According to the FDA, Breakthrough Therapy designation is given when preliminary clinical evidence has been provided to show that a treatment effect may represent substantial improvement over available therapies for the treatment of a serious condition.
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Otomagnetics Reduces Cisplatin-Related Hearing Loss in Mice, New Study Shows
Using a new technique to deliver steroids to the inner ear, developed with funding from Action on Hearing Loss, Otomagnetics has been able to reduce hearing loss in mice treated with the chemotherapy drug cisplatin by 50%.
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Sensorion Receives Orphan Drug Designation for Chemotherapy-Induced, Hearing Loss Treatment
The drug is a therapy in development for the treatment of hearing disorders, for the prevention of Platinum-Induced Ototoxicity in pediatric patients.
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Sound Pharmaceuticals Receives Award for Drug Used to Treat Hearing Loss in Cystic Fibrosis Patients
Sound Pharmaceuticals announced that the company has been awarded up to $1.6 million for their development of a drug used to treat ototoxicity in patients with cystic fibrosis.
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Otonomy Enrolls Patients for Phase 2 Trial of OTO-104 for Prevention of Hearing Loss During Chemotherapy
Otonomy has announced the enrollment of the first patients in a Phase 2 clinical trial evaluating OTO-104 for the prevention of hearing loss in cancer patients undergoing chemotherapy with platinum-based agents.
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