Tag: hair cells

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Mass Eye and Ear Researchers Awarded $12.5 Million Grant

A team of Mass Eye and Ear researchers in the Eaton-Peabody Laboratories have been awarded a five-year, $12.5 million P50 Clinical Research Center Grant from the National Institute on Deafness and Other Communicable Disorders (NIDCD) of the National Institutes of Health (NIH) to continue their research on cochlear synaptopathy, or hidden hearing loss, a type of hearing damage first discovered at Mass Eye and Ear in 2009.

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Researchers Create Inner Ear Sound Frequency Map

Researchers at Uppsala University have created the “first 3D map of the hearing nerve showing where the various sound frequencies are captured,” according to an article on the university's website. Using what is known as synchrotron X-ray imaging, they were able to trace the fine nerve threads and the vibrating auditory organ, the cochlea, and find out exactly how the frequencies of incoming sound are distributed.

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USC Researchers Produce Sensory Hearing Cells

To achieve reprogramming, the scientists exposed fibroblasts and supporting cells to a cocktail of four transcription factors, which are molecules that help convey the instructions encoded in DNA. The scientists identified this cocktail by testing various combinations of 16 transcription factors that were highly active in the hair cells of newborn mice.

Researchers Map Functioning of Inner Ear

A team led by Professor Karen B. Avraham, vice dean of the Sackler Faculty of Medicine at Tel Aviv University, has now created the first map of “methylation”–one of the body’s main epigenetic signals–that reflects the functioning of the inner ear in its entirety.

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