Researchers Use Organoid-on-a-Chip to Model Inner Ear Development
The system aims to provide insight into sensory hair cell development and potential pathways for regeneration.
The system aims to provide insight into sensory hair cell development and potential pathways for regeneration.
The three-day virtual event, hosted by HHTM, will provide attendees with insights into the latest treatment and technologies that will have a hand in shaping the future of hearing care.
Researchers examined 120 inner ears collected at autopsy. They used multivariable statistical regression to compare data on the survival of hair cells, nerve fibers, and the stria vascularis with the patients' audiograms to uncover the main predictor of the hearing loss in this aging population. They found that the degree and location of hair cell death predicted the severity and pattern of the hearing loss, while stria vascularis damage did not.
Otonomy intends to complete the clinical development to support registration of OTIVIDEX in the United States for patients with Ménière’s disease, and will advance multiple programs for the prevention and treatment of sensorineural hearing loss, and the treatment of tinnitus.
Read MoreCell biologist Benjamin J. Perrin of the School of Science at Indiana University-Purdue University Indianapolis (IUPUI) is advancing knowledge of age-related hearing loss with the goal of informing possible therapeutic cell-regeneration approaches to the often-debilitating problem.
Read MoreThe presentation described a process that may provide a novel means of addressing cellular deficiencies or malfunctions in many diseases including hearing loss, dermatology, muscle, and gastrointestinal (GI) diseases.
Read MoreThe Brain Channel, a University of California Television (UCTV) program that features segments on issues and research related to the brain and nervous system, premiered “Inner Ear Treatments, Cochlear Implants, Hearing Loss, and More: Advances in Otolaryngology with Jeffrey P. Harris-On Our Mind,” on their website.
Read MoreThe Brain Channel, a University of California Television (UCTV) program that features segments on issues and research related to the brain and nervous system, premiered “Inner Ear Treatments, Cochlear Implants, Hearing Loss, and More: Advances in Otolaryngology with Jeffrey P. Harris-On Our Mind,” on their website.
Read MoreResearchers at the University of Kentucky and the University of Kentucky (UK) College of Medicine have isolated a mechanism necessary for stabilizing hair cells in the ear, according to an article in UKnow. The research was published online in eLife on March 28.
Read MoreSt Jude Children’s Research Hospital investigators have used genetic manipulation to regenerate auditory hair cells in adult mice, the hospital announced. The research marks a possible advance in treatment of hearing loss in humans.
Read MoreStrekin AG, Basal, Switzerland, announced that the European Medicines Agency (EMA) has granted orphan drug designation for the use of STR001 in the treatment of sudden sensorineural hearing loss, or sudden deafness.
Read MoreA Creighton University researcher has discovered a new technique for controlling gene expression to aid in the regeneration of sensory hair cells in the inner ear to potentially restore hearing and balance.
Read MoreAccording to new research findings, blocking the Notch pathway that controls hair cell distribution in the inner ear may help determine cochlear progenitor cell proliferation capacity.
Read More